首页|全肝CT灌注成像血流动力学参数对巨块型肝癌TACE疗效的评估价值

全肝CT灌注成像血流动力学参数对巨块型肝癌TACE疗效的评估价值

Evaluation Value of Hemodynamic Parameters of Whole Liver CT Perfusion Imaging in TACE Efficacy of Massive Liver Cancer

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目的 分析全肝CT灌注成像血流动力学参数对巨块型肝癌患者经动脉化疗栓塞术(transarterial chemoemboliza-tion,TACE)疗效的评估价值.方法 回顾分析安阳市人民医院2022 年11 月至2023 年7 月收治的75 例(98 个病灶)接受TACE治疗的巨块型肝癌患者资料,所有患者术后1 个月均接受肝脏CT灌注成像(hemodynamic parameters of whole liver CT perfusion imaging,HCTPI)及数字减影血管造影(digital subtraction angiography,DSA)检查,记录血流动力学参数并分析评估TACE疗效效能.结果 75 例患者共 98 个病灶,TACE术后DSA检查显示存在 61 个残瘤染色.HCTPI评估TACE术后疗效灵敏度、特异度、准确率分别为 88.52%、94.59%、90.82%.残留病灶肝动脉灌注量(hepatic arterial perfusion,HAP)、肝动脉灌注指数(hepatic perfusion index,HPI)高于背景肝实质,门静脉灌注量(portal venous perfusion,PVP)、总肝灌注量(total liver perfusion,TLP)低于背景肝实质,差异均有统计学意义(P<0.05).结论 不同性质肝组织间HCTPI血流动力参数差异明显,巨块型肝癌患者TACE术后接受HCTPI检查有助于评估治疗效果.
Objective To analyze the evaluation value of whole liver CT perfusion imaging hemodynamic parameters for the effi-cacy of transarterial chemoembolization(TACE)in patients with massive liver cancer.Methods The data of 75 patients with massive liver cancer(98 lesions)who received TACE treatment in Anyang People's Hospital from November 2022 to July 2023 were retrospec-tively analyzed.All patients received hemodynamic parameters of whole liver CT perfusion imaging and digital subtraction angiography 1 month after surgery.Hemodynamic parameters were recorded and the efficacy of TACE was evaluated.Results There were 98 le-sions in 75 patients,and DSA examination after TACE showed 61 residual tumor staining.The sensitivity,specificity and accuracy of HCTPI were88.52%,94.59%and 90.82%,respectively.hepatic arterial perfusion(HAP)and hepatic perfusion index(HPI)were higher than those of background hepatic parenchyma,and portal venous perfusion(PVP),total liver perfusion(TLP)were low-er than those on the background liver parenchyma,with statistical significance(P<0.05).Conclusion HCTPI hemodynamic pa-rameters differ significantly among liver tissues of different nature.HCTPI examination after TACE in patients with massive liver cancer is helpful to evaluate the therapeutic effect.

whole liver CT perfusion imaginghemodynamic parametersmassive liver cancerTACEcurative effect

吕晓婷、张尧

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安阳市人民医院放射影像科,河南 安阳 455000

全肝CT灌注成像 血流动力学参数 巨块型肝癌 经动脉化疗栓塞术 疗效

2024

锦州医科大学学报
辽宁医学院

锦州医科大学学报

影响因子:0.802
ISSN:1674-0424
年,卷(期):2024.45(4)
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