Analysis of Risk Factors of Anastomotic Leakage After Laparoscopic Assisted Radical Gastrectomy
Objective To investigate the risk factors of anastomotic leakage(AL)after laparoscopic assisted radical gastrectomy for gastric cancer.Methods Clinical data of 281 patients who underwent laparoscopic-assisted radical gastectomy in the Department of General Surgery of Linyi People's Hospital from January 2022 to December 2023 were retrospectively analyzed.According to the occurrence of AL,they were divided into AL group(n=14)and non-AL group(n=267).Relevant clinical data were collected.x2 test was used for univariate analysis and binary Logistic regression analysis was used for multivariate analysis.P＜0.05 was considered statistically significant.Results In this study,AL occurred in 14 patients after laparoscopic assisted radical gastrectomy,with an incidence of 4.98％.Univariate analysis showed that there were significant differences in age,preoperative pulmonary insufficiency,preoperative history of neoadjuvant therapy,tumor invasion of cardiac,resection degree,and intraoperative blood loss(P＜0.05).The results of multivariate analysis suggested that the age of the patient(P=0.007),the tumor invasion of the cardia(P=0.015),and the degree of resection(P=0.003)were independent risk factors for AL after laparoscopic assisted radical gastrectomy(P＜0.05).Conclusion Age no less than 65 years old,tumor invasion of the cardia and total gastrectomy are independent risk factors for AL after laparoscopic assisted radical gastrectomy.Surgeons should take certain preventive measures against these factors in order to reduce the incidence of AL.
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