Analysis on the Effect of Antiretroviral Therapy on HIV/AIDS Patients in Pingdingshan City of Henan Province from 2004 to 2022
Objective To provide scientific basis for HIV/AIDS prevention and treatment in Pingdingshan by ana-lyzing the status of antiretroviral therapy among HIV/AIDS patients from 2004 to 2022 and evaluating the effect of antiretroviral therapy.Methods To download data on HIV/AIDS patients who have been receiving antiviral treat-ment for more than 6 months current address in Pingdingshan City from 2004 to 2022,through the"China Disease Prevention and Control Information System".CD4+T lymphocytes and viral load were detected as immunological and virological evaluation indicators of antiviral treatment effect respectively.SPSS 22.0 was applied for statistical analysis of the data.Results A total of 2 186 patients were enrolled which the baseline CD4+T lymphocyte count was(286.32±189.81)/μl before treatment.The mean CD4+T lymphocyte count was(446.45±221.96)/μl during the last follow-up after antiviral therapy.There was significant difference in the distribution of CD4+T lymphocyte be-fore and after antiviral treatment(x2=641.53,P＜0.001).There were 1 875(85.77％)patients with VL＜20 copies/ml at the last follow-up,and the constituent ratio was gradually increasing(x2=16.970,P＜0.001).Spearman test showed a negative correlation between CD4+T lymphocyte and VL(r=-0.143,P＜0.001).Conclusion The antivi-ral treatment HIV/AIDS patients under treatment in Pingdingshan have good immune reconstitution and virus sup-pression.We should continue to expand detection,early detection and early treatment,strengthen patient compli-ance education,adhere to long-term standardized treatment,and further improve the quality of antiviral treatment.
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