Epidemiological Investigation and Analysis of the First Human Case Infection with Streptococcus Suis in Tengzhou City
Objective To provide a basis for preventing and controlling the epidemic by identifying the source and transmission route of the first human case infection with Streptococcus suis in Tengzhou City.Methods Con-duct investigations by inquiring about medical and epidemiological history,clinical manifestations,and conducting laboratory tests such as isolating Streptococcus suis through blood culture.Results The patient is a 48-year-old female with a history of splenectomy,and acute onset on July 14,2022,with symptoms of systemic infection and neurological toxicity.On July 18,the test report showed that the drug sensitivity test was Streptococcus suis.The pa-tient had no clear history of contact with dead pigs and had a history of buying and eating pork before the onset of the disease.The patient's clinical symptoms were in line with toxic shock syndrome(shock,liver and kidney dam-age,coagulation dysfunction).Combined with blood culture results,it was considered that she were in line with hu-man infection with Streptococcus suis.On July 21,the Provincial Center for Disease Control and Prevention con-ducted a retest and identified positive results for Streptococcus suis type 2.The patient died on July 24 due to mul-tiple organ failure and failed rescue efforts.Conclusion The patient confirmed human infection with Streptococ-cus suis by laboratory examination(Streptococcus suis type 2),and the pathogen may have been infected through damaged skin wounds.Monitoring the epidemic situation in live pigs,strengthening management and personal pro-tection are the main measures to prevent and control human infection with Streptococcus suis.