红细胞体积分布宽度与新生儿脓毒症严重程度的相关性分析
Correlation Analysis of Red Cell Volume Distribution Width with the Severity of Neonatal Sepsis
杨欣1
作者信息
- 1. 赣南医学院第一附属医院,江西 赣州 341000
- 折叠
摘要
目的:探讨红细胞体积分布宽度(red cell volume distribution width,RDW)与新生儿脓毒症(neonatal sepsis)病情严重程度的相关性,为临床准确判断新生儿脓毒症的严重程度提供参考.方法:选取 2019 年 7 月—2022 年 5 月赣南医学院第一附属医院收治的 55 例新生儿脓毒症患儿作为研究对象,根据新生儿危重病例评分(neonatal critical illness score,NCIS)将患者分为非危重组(n=17)、危重组(n=33)和极危重组(n=5),分析患儿RDW水平与C反应蛋白(C-reactive protein,CRP)、病情危重程度的相关性.结果:Kruskal-Wallis H检验结果显示,非危重组、危重组和极危重组患儿的RDW、CRP水平经两两比较其差异均有统计学意义(P＜0.05);而Spearman秩相关分析结果显示,脓毒症患儿的RDW水平与其病情严重程度正相关(rs=0.746,P＜0.001),与其CRP水平亦正相关(rs=0.779,P＜0.001).结论:新生儿脓毒症的严重程度与患儿RDW水平密切相关,并且RDW水平越高病情越严重.
Abstract
Objective:To investigate the correlation of red cell volume distribution width(RDW)with the severity of neonatal sepsis,and to provide reference for accurately judging the severity of neonatal sepsis in clinical practice.Methods:55 child patients with neonatal sepsis admitted to the First Affiliated Hospital of Gannan Medical University from July 2019 to May 2022 were selected as the research subjects.According to the neonatal critical illness score(NCIS),the patients were divided into non-critical group(n=17),critical group(n=33),and extremely critical group(n= 5).The correlation between RDW level in the child patients and C-reactive protein(CRP)and the severity of condition was analyzed.Results:The Kruskal-Wallis H test results showed that there were statistically significant differences in RDW and CRP levels among the child patients in non-critical,critical and extremely critical groups after pairwise comparison(P＜0.05).The Spearman rank correlation analysis results showed that the RDW level in the child patients with sepsis was positively correlated with their severity of condition(rs=0.746,P＜0.001),and also positively correlated with their CRP level(rs=0.779,P＜0.001).Conclusion:The severity of neonatal sepsis is closely related to the RDW level in child patients,and the higher the RDW level is,the more severe the condition is.
关键词
新生儿脓毒症/红细胞体积分布宽度/C反应蛋白Key words
neonatal sepsis/red cell volume distribution width/C-reactive protein引用本文复制引用
出版年
2023
NETL
NSTL
维普
万方数据