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某院碳青霉烯类抗菌药物的合理用药分析

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目的:分析医院碳青霉烯类抗菌药物的合理用药情况,为促进临床碳青霉烯类药物的合理使用提供参考。方法:选取 2022 年 7 月—12 月郑州市第二人民医院住院患者的碳青霉烯类药物医嘱作为研究资料,采集患者的临床诊断、检查结果,以及所用碳青霉烯类药物的品种、用法用量、疗程、联用药物等信息,依据《碳青霉烯类抗菌药物临床应用评价细则》对碳青霉烯类药物医嘱进行合理用药评价并进行分析。结果:2022 年 7 月—12 月医院共有 84 例次患者使用了碳青霉烯类药物,其涉及的临床科室主要有重症医学科(33 例次,占 39。29%)、呼吸与危重症医学科(12 例次,占 14。29%)和消化内科二(10 例次,占 11。90%);合理用药点评结果显示,84 例次患者中共发现 41 条不合理用药情况,其中主要为适应证不适宜(16 条,占 39。02%)和用药前未进行病原学送检(14 条,占34。15%)。结论:当前医院住院患者碳青霉烯类抗菌药物的使用仍存在较多的不合理现象,管理部门应当加强对临床的培训和管理,以提高其合理用药水平,最终保障患者用药的安全和有效。
Analysis of Rational Use of Carbapenem Antibacterial Drugs in a Hospital
Objective:To analyze the rational use of carbapenem antibacterial drugs in a hospital and provide reference for promoting the clinical rational use of carbapenems.Methods:The carbapenem medical orders of inpatients in Zhengzhou Second People's Hospital from July to December 2022 were selected as the research data,and the information such as patient's clinical diagnosis and examination results,type of carbapenem used,usage and dosage,course of treatment and drug combination was collected.The rational use of carbapenems in medical orders was evaluated and analyzed according to the Detailed Rules for the Clinical Application Evaluation of Carbapenem Antibacterial Drugs.Results:From July to December 2022,84 patients used carbapenems in the hospital,and the clinical departments involved mainly included Department of Critical Care Medicine(33 cases,39.29%),and Department of Respiratory and Critical Care Medicine(12 cases,14.29%)and Department of Gastroenterology Ⅱ(10 cases,11.90%);the results of comments on the rational drug use revealed that there were a total of 41 irrational drug uses in 84 patients,mainly including inappropriate indications(16 items,39.02%)and no pathogenic testing before medication(14 items,34.15%).Conclusion:Currently,there are still many unreasonable phenomena in the use of carbapenem antibacterial drugs in inpatients in the hospital.The administrative department should strengthen the clinical training and management to improve the rational drug use and ultimately ensure the medication safety and effectiveness for patients.

carbapenemsantibacterial drugsrational drug usecomments on medical orders

韩红玉、陈耀升、张英杰、段晓颖

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河南中医药大学第一附属医院,郑州 450000

郑州市第二人民医院,郑州 450000

碳青霉烯类药物 抗菌药物 合理用药 医嘱点评

2024

抗感染药学
江苏省苏州市第五人民医院

抗感染药学

影响因子:0.505
ISSN:1672-7878
年,卷(期):2024.21(1)
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