Objective:To analyze the rational use of carbapenem antibacterial drugs in a hospital and provide reference for promoting the clinical rational use of carbapenems.Methods:The carbapenem medical orders of inpatients in Zhengzhou Second People's Hospital from July to December 2022 were selected as the research data,and the information such as patient's clinical diagnosis and examination results,type of carbapenem used,usage and dosage,course of treatment and drug combination was collected.The rational use of carbapenems in medical orders was evaluated and analyzed according to the Detailed Rules for the Clinical Application Evaluation of Carbapenem Antibacterial Drugs.Results:From July to December 2022,84 patients used carbapenems in the hospital,and the clinical departments involved mainly included Department of Critical Care Medicine(33 cases,39.29%),and Department of Respiratory and Critical Care Medicine(12 cases,14.29%)and Department of Gastroenterology Ⅱ(10 cases,11.90%);the results of comments on the rational drug use revealed that there were a total of 41 irrational drug uses in 84 patients,mainly including inappropriate indications(16 items,39.02%)and no pathogenic testing before medication(14 items,34.15%).Conclusion:Currently,there are still many unreasonable phenomena in the use of carbapenem antibacterial drugs in inpatients in the hospital.The administrative department should strengthen the clinical training and management to improve the rational drug use and ultimately ensure the medication safety and effectiveness for patients.
关键词
碳青霉烯类药物/抗菌药物/合理用药/医嘱点评
Key words
carbapenems/antibacterial drugs/rational drug use/comments on medical orders