Research Progress in Biologically Targeted Therapy of Psoriasis
Psoriasis is an immune-mediated,polygenic,hereditary skin disease.Although the disease is generally not fatal,it seriously affects the living quality of patients.Presently,the treatment measures of infection are effective,but it is not easy to achieve long-term remission.In recent years,targeted biologics and oral small molecule drugs have become a new focus in the treatment of psoriasis, which can regulate pathological immune responses, reduce the inflammation and recurrence rate more effectively than traditional therapeutic methods. In this article, the pathogenesis of psoriasis, the research and development and clinical applications of targeted biologics and oral small molecule drugs are reviewed to provide the latest perspective for better treatment of psoriasis.