Analysis of Diagnosis and Treatment of Male Patients with Erythema Multiforme Drug Eruption on External Genitalia Caused by Artificial Bezoar Metronidazole Capsules
Objective:To analyze the diagnosis and treatment process of one male patient with erythema multiforme drug eruption on the external genitalia caused by artificial bezoar metronidazole capsules,and provide reference for the clinical medication safety of such drugs.Methods and Results:The patient purchased and took artificial bezoar metronidazole capsules on his own because of toothache.However,on the second day,rice-to-bean-sized erythemas were found on his external genitalia,which were densely and symmetrically distributed with slight itching,so he discontinued the drugs on his own.Nonetheless,his symptoms were not relieved after discontinuing medication for many days,and the skin lesions gradually increased,and erosion and exudation appeared on the surfaces,so he was admitted to the hospital for treatment.After admission,the patient was given anti-inflammatory and anti-infective treatment.After 2 weeks,the patient's erythema basically disappeared;one month later,the patient's skin lesions were basically healed;during the period,the doctor used the Naranjo's Assessment Scale to investigate the correlation between erythema multiforme drug eruption and artificial bezoar metronidazole capsules.The assessment score was 6,i.e.the correlation was"very likely".Conclusion:It is rare for drug eruptions caused by artificial bezoar metronidazole capsules to appear on the external genitalia only without involving other body parts.Medication instructions should be given during clinical propaganda and education to facilitate early identification and early treatment for patients.
artificial bezoar metronidazole capsulesmale patientexternal genitaliaerythema multiforme drug eruptionadverse drug reactions
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