首页|某院门诊阿奇霉素处方的调查与分析

某院门诊阿奇霉素处方的调查与分析

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目的:调查医院门诊阿奇霉素处方的临床特点,并对阿奇霉素开展专项的处方点评,为临床阿奇霉素的合理使用提供参考。方法:利用医院信息系统,调取 2023 年 8 月 1 日—10 月 31 日常熟市第一医院门诊的190 729 张处方作为研究资料,采集处方中患者的年龄、性别、科室、诊断,以及药品的种类、数量、金额等信息,并依据《处方管理办法》、《医院处方点评管理规范(试行)》、药品说明书和相关治疗指南等权威资料对阿奇霉素开展专项的处方点评,分析阿奇霉素处方的临床特点和不合理使用状况。结果:190 729 张处方中抗菌药物处方有23 780 张,其中阿奇霉素处方有 4 968 张(占 20。89%),而这其中阿奇霉素的剂型主要为干混悬剂(3 588 张,占72。22%);4 968 张阿奇霉素处方中,在科室分布上以儿科及新生儿科为主(4 340 张,占 87。36%),患者的年龄以未成年(<18 岁)为主(4 455 张,占 89。67%),患者的诊断以呼吸系统疾病为主(4 409 张,占 88。75%),在用药数量上以 2 种(1 548 张,占 31。16%)和 3 种(1 172 张,占 23。59%)为主,在药品金额上以抗菌药物(172 046 元,占 28。01%)和中成药(164 478 元,占 26。78%)的占比最高;4 968 张阿奇霉素处方中存在与其他抗菌药物联用的有 510 张,其中以与头孢菌素联用为最多(492 张,占 96。47%);处方点评发现,有 330 张处方存在不合理用药情况(不合理率为6。64%),其中主要的不合理原因为处方药品数超 5 种(137 张,占 41。52%)和用法用量不适宜(94 张,占 28。48%)。结论:阿奇霉素在医院门诊使用较为广泛,用药情况整体较为合理,但大处方情况较为突出,对此医院应加强相关的培训和管理,以提高临床的合理用药水平。
Investigation and Analysis of Azithromycin Prescriptions in Outpatient Department of a Hospital
Objective:To investigate the clinical characteristics of azithromycin prescriptions in the outpatient department of a hospital and conduct special comments on azithromycin prescriptions,and provide reference for the clinical rational use of azithromycin.Methods:By using the hospital information system,190 729 prescriptions from the outpatient department of Changshu No.1 People's Hospital from August 1 to October 31,2023 were retrieved as the research materials,and the information in the prescriptions such as patient's age,gender,department,diagnosis,type,quantity and amount of drugs was collected,and special comments on azithromycin prescriptions were performed according to the Measures on Administration of Prescriptions,the Management Standard of Comments on Hospital Prescriptions(Trial),package inserts and related treatment guidelines and other authoritative data,to analyze the clinical characteristics and irrational use of azithromycin prescriptions.Results:Among 190 729 prescriptions,there were 23 780 prescriptions for antibacterial drugs,including 4 968 azithromycin prescriptions(20.89%),and the dosage form of azithromycin was mainly dry suspension(3 588 prescriptions,72.22%).Among 4 968 azithromycin prescriptions,in terms of department distribution,the pediatrics department and neonatology department were dominated(4 340 prescriptions,87.36%);in terms of age distribution,minors(below 18 years old)were dominated(4 455 prescriptions,89.67%);in terms of diagnosis of patients,respiratory diseases were dominated(4 409 prescriptions,88.75%);in terms of quantity of drugs,2 types(1 548 prescriptions,31.16%)and 3 types(1 172 prescriptions,23.59%)were dominated;in terms of drug amount,antibacterial drugs(172 046 yuan,28.01%)and Chinese patent medicines(164 478 yuan,26.78%)were dominated.Among 4 968 azithromycin prescriptions,there was combination with other antibacterial drugs in 510 prescriptions,of which combination with cephalosporins was the most(492 prescriptions,96.47%).The comments on prescriptions revealed that 330 prescriptions contained irrational drug use(irrational rate of 6.64%),of which the main irrational reasons were more than 5 types of prescription drugs(137 prescriptions,41.52%)and inappropriate usage and dosage(94 prescriptions,28.48%).Conclusion:Azithromycin is widely used in the outpatient department of hospital,and the overall medication is rational,nut the extraordinary prescription is more prominent.Therefore,relevant training and management should be strengthened in hospitals to improve the level of clinical rational drug use.

azithromycinoutpatient prescriptionmedication characteristicsrational drug use

谭骏、王建、张桂芬

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常熟市第一人民医院(苏州大学附属常熟医院)药剂科,江苏 常熟 215500

阿奇霉素 门诊处方 用药特点 合理用药

2024

抗感染药学
江苏省苏州市第五人民医院

抗感染药学

影响因子:0.505
ISSN:1672-7878
年,卷(期):2024.21(2)
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