Epidemiological Analysis of Adverse Drug Reactions Reported by a Hospital
Objective:To analyze the occurrence characteristics and patterns of adverse drug reactions(ADRs)reported by a hospital and provide reference for safe and rational medications in the clinics.Methods:A total of 311 ADR reports reported by Puyang Anyang District Hospital to the National Adverse Drug Reaction Monitoring System from July 2022 to June 2023 were used as research data,and the information such as the types and involved organs of ADR reports,the age and gender of involved patients and the types and dosage forms of involved drugs,etc.was collected,to analyze the occurrence characteristics and patterns of ADRs in the hospital.Results:Among the 311 ADR reports,the report types were mainly"ordinary"(271 cases,87.14%),while the types of"serious"(22 cases,7.07%)and"new and ordinary"(16 cases,5.14%)were less;in terms of gender,females were slightly more than males(164 cases vs 147 cases);in terms of age,ADRs mainly occurred in people aged above 40 years(260 cases,83.60%);in terms of drugs,311 ADRs involved 107 types of drugs in 12 categories,mainly drugs for central nervous system(60 cases,19.29%),cardiovascular system(53 cases,17.04%),and anti-infective drugs(50 cases,16.08%);the dosage forms of drugs were mainly injections(194 cases,62.38%),followed by powder injections(88 cases,28.30%);in terms of organs involved,311 ADRs mainly involved the gastrointestinal system(76 cases,24.44%),skin and its appendages(56 cases,18.01%)and nervous system(53 cases,17.04%).Conclusion:ADRs reported by the hospital mainly occur in middle-aged and elderly people aged above 40 years,and the drugs used are mostly injections.Although new or serious ADRs occur less frequently,clinical monitoring after medications should still be performed to ensure the medication safety of patients.
adverse drug reactionsepidemiological characteristicsrational drug use