Analysis of Clinical Characteristics of Adverse Drug Reactions Caused by Drotaverine Injection
Objective:To analyze the clinical characteristics of adverse drug reactions(ADRs)caused by drotaverine injection,and provide reference for the clinical medication safety of drotaverine injection.Methods:The reports of 64 cases with ADRs caused by drotaverine injection submitted by Suzhou Kowloon Hospital from January 2019 to December 2021 were collected as the research materials;the information such as patient's age,gender,usage and dosage of drotaverine injection,as well as occurrence time,clinical manifestations and final outcomes of ADRs was collected to analyze the occurrence characteristics and rules of ADRs caused by drotaverine injection.Results:Among 64 cases with ADRs caused by drotaverine injection,patients aged 20 to 40 years accounted for the highest proportion(45 cases,70.31%),the single dose of drotaverine was mostly 80 mg(58 cases,90.62%),the occurrence time of ADRs was mainly within 30 minutes after medication(45 cases,70.31%),and the organs involved by ADRs were mainly the skin and its appendages(61 cases,incidence of 95.31%).Regarding outcomes of patients,the symptoms of 52 patients relieved spontaneously after discontinuing drotaverine injection,and the remaining 12 patients also improved after symptomatic treatment.Conclusion:ADRs caused by drotaverine injection have obvious characteristics in terms of patient's age,dosage of administration,occurrence time and organs involved.Clinical monitoring should be strengthened for related patients to ensure their medication safety.
drotaverine injectionadverse drug reactionsclinical characteristics
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