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泉州地区献血者细小病毒B19感染的流行病学分析

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目的:分析泉州地区献血者细小病毒B19 感染的发生情况及其特点,为临床的用血安全提供参考。方法:选取 2021 年 10 月—2022 年 4 月泉州市中心血站采集到的 5 026 份献血者的献血血样作为研究资料,对其进行细小病毒B19 的核酸试验筛检(nucleic acid testing,NAT),随后再随机抽取 800 份血样进行细小病毒B19 的免疫球蛋白G(immunoglobulin G,IgG)和免疫球蛋白M(immunoglobulin M,IgM)抗体检测,分析献血者细小病毒B19 感染的发生情况及其特点。结果:5 026 份献血者血样的细小病毒B19 的NAT结果均为阴性,阴性率为100。00%;800 份血样的细小病毒B19 抗体检测结果显示,有 134 份的抗体检测结果为阳性(阳性率为 16。75%),其中IgG阳性 111 份、IgM阳性有 28 份(IgG、IgM双阳的有 5 份);流行病学分析显示,女性、>35~45 岁群体、山区人民和农民的抗体阳性率较高(P<0。05)。结论:此次泉州地区献血者的血样并未检出细小病毒B19 感染的情况,但鉴于抗体检查中有部分样品呈阳性,血站仍有进行常态化检查的必要,以确保患者的用血安全。
Epidemiological Analysis of Parvovirus B19 Infection in Blood Donors in Quanzhou Area
Objective:To analyze the occurrence and characteristics of parvovirus B19 infection in blood donors in Quanzhou area,and provide reference for clinical blood use safety.Methods:A total of 5 026 blood samples collected from blood donors in Quanzhou Central Blood Station from October 2021 to April 2022 were selected as research data for nucleic acid testing(NAT)of parvovirus B19.Subsequently,800 blood samples were randomly selected for testing for immunoglobulin G(IgG)and immunoglobulin M(IgM)antibodies against parvovirus B19,and the occurrence and characteristics of parvovirus B19 infection in blood donors were analyzed.Results:The NAT results of parvovirus B19 in 5 026 blood samples from blood donors were all negative,with a negative rate of 100.00%;the testing results of parvovirus B19 antibodies in 800 blood samples showed that 134 of them were positive(with a positive rate of 16.75%),of which 111 were IgG positive and 28 were IgM positive(5 were both IgG and IgM positive);epidemiological analysis showed that the antibody positive rate was higher among women,the population aged over 35-45,people in mountainous areas,and farmers(P<0.05).Conclusion:No parvovirus B19 infection is detected in the blood samples from blood donors in Quanzhou area this time.However,considering that some samples are positive in antibody test,it is still necessary for the blood station to conduct regular tests to ensure the blood use safety of patients.

parvovirus B19 infectionblood donorsepidemiological characteristicsnucleic acid test screeningQuanzhou area

张璇、王文杰、林奕丽

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泉州市中心血站检验科,福建 泉州 362000

细小病毒B19 感染 献血者 流行病学特点 核酸试验筛检 泉州地区

福建省泉州市科技计划

2020N66S

2024

抗感染药学
江苏省苏州市第五人民医院

抗感染药学

影响因子:0.505
ISSN:1672-7878
年,卷(期):2024.21(3)
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