Analysis of Epidemiological Characteristics of MDRO Infections in Hospitalized Patients and Their Treatment Outcomes after Receiving Pharmaceutical Care in a Hospital
Objective:To analyze the epidemiological characteristics of multidrug-resistant organism(MDRO)infections in hospitalized patients and their treatment outcomes after receiving pharmaceutical care in a hospital,and provide reference for the treatment of clinical patients with MDRO infections.Methods:A total of 1 586 hospitalized patients admitted to Puyang Oilfield General Hospital from January 2020 to December 2022 were selected as the research objects,and the information of these patients such as age,gender,department,microbial examination results,etc.was collected,to analyze the epidemiological characteristics of MDRO infections in the hospitalized patients,and compare the impact of pharmaceutical care on the treatment outcomes of patients with MDRO infections.Results:Among the 1 586 hospitalized patients,226 had MDRO infections,with an incidence of 14.25%;a total of 238 strains of pathogenic bacteria were detected in the specimens of 226 patients with MDRO infections,mainly including Escherichia coli(98 strains,41.18%),followed by Klebsiella pneumoniae(35 strains,14.71%),Staphylococcus hemolyticus(23 strains,9.66%)and Staphylococcus aureus(20 strains,8.40%);the 226 patients with MDRO infections were primarily from surgery department(61 cases,26.99%),ICU(56 cases,24.78%)and neurosurgery(45 cases,19.91%);the specimens of pathogenic bacteria were mainly sputum(84 cases,37.17%),pus(51 cases,22.57%)and urine(38 cases,16.81%).The proportion of MDRO patients with good treatment outcomes who received pharmaceutical care was significantly higher than that of MDRO patients who did not receive pharmaceutical care(87.61%vs 76.11%,P<0.05).Conclusion:The pathogenic bacteria in patients with MDRO infections in the hospital are primarily Gram-negative bacteria such as Escherichia coli and Klebsiella pneumoniae,which are mainly distributed in the surgery department and ICU and special attention should be paid to them clinically;in addition,the pharmaceutical care can help patients with MDRO infections to achieve more effective treatment;therefore,it can be considered to include clinical pharmacists in the multidisciplinary collaborative team to improve the clinical service levels and allow patients to receive better treatment.
multidrug-resistant organism infectionsdistribution of pathogenic bacteriaepidemiological characteristics,pharmaceutical caretreatment outcomes
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