Research Progress in the Pharmacological Effects and Mechanisms of Berberine against Gastric Cancer
Gastric cancer is an important killer that threatens people's life and health,and its morbidity and mortality rank third among various malignant tumors in China.In addition to its anti-inflammatory,anti-infective,and cardiovascular regulating effects,berberine has good effects on liver cancer,colorectal cancer,brain tumors,head and neck tumors,urinary system tumors,etc.Therefore,it may be a potential anti-tumor drug.In this article,the prevention of gastric cancer with berberine,and the inhibition and induction of apoptosis of human gastric cancer cells such as SGC7901,BGC-823,and MKN-45 are mainly reviewed to provide a reference for the clinical development of berberine in the future.
berberineanti-tumor effectgastric cancermechanism of actionresearch progress
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