Clinical Analysis of a Patient with Systemic Muscle Pain Caused by Ceftizoxime Sodium for Injection
Objective:To analyze the occurrence and treatment process of systemic muscle pain in one patient after using ceftizoxime sodium for Injection,and to provide reference for clinical medication safety of ceftizoxime.Methods and Results:The patient was referred to the gastrointestinal surgery department of our hospital because of repeated middle and upper abdominal pain and discomfort for more than 20 days,and gastric cancer(cardiac adenocarcinoma)detected by other hospital.The clinic considered elective surgery,so ceftizoxime sodium for Injection was preventively used.However,shortly after medication,the patient complained of systemic muscle soreness,night sweating,joint discomfort,and extensive pain in the back and waist,with a heart rate of 104 times/min and a visual analysis scale(VAS)of 8 points.Based on the previous condition and current medication of the patient,it was initially suspected that the adverse drug reactions were caused by ceftizoxime sodium for Injection,so ceftizoxime sodium for Injection was stopped.Soon,the patient complained that the systemic myalgia was relieved and VAS was reduced to 3 points,so it was determined that the myalgia was probably caused by ceftizoxime sodium for Injection.Conclusion:Systemic muscle pain caused by ceftizoxime sodium for Injection is rarely reported in clinical practice.Clinical pharmacists should integrate patients'condition and medication when carrying out pharmaceutical practice to help doctors make accurate judgments,so as to effectively deal with situations and ensure the medication safety of patients.
ceftizoxime sodiumsystemic muscle painadverse drug reactions
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