Analysis of Pharmaceutical Care for Anti-infective Therapy in One Patient with Right-sided Infective Endocarditis Complicated by Infection at Other Sites
Objective:To analyze the pharmaceutical care for anti-infective therapy in one patient with right-sided infective endocarditis(IE)complicated by infection at other sites,and provide a reference for the anti-infective therapy of similar patients in clinical practice.Methods and Results:The patient was admitted to the Hospital due to intermittent fever for nearly a month,and was preliminarily diagnosed with pulmonary infection clinically due to occasional coughing and expectoration.Empiric treatment with piperacillin-tazobactam sodium was administered.Upon completion of the admission examination,it was clinically considered,based on the results of the cardiac color ultrasonography,that a right-sided IE was present.Accordingly,the clinical pharmacist recommended the addition of vancomycin for the methicillin-resistant Staphylococcus aureus(MRSA);but in consideration of gradual alleviation of the fever,the recommendation was not adopted.However,the patient developed a fever a week later,and Staphylococcus aureus was detected in the blood culture.Considering the renal function of the patient,linezolid and levofloxacin were administered clinically.Two days later,in consideration of the improved renal function,vancomycin was administered instead.Shortly after,the patient's fever symptoms improved significantly.In addition,given that candida parapsilosis was repeatedly detected in the urine fungal culture recently,fluconazole was added for treatment,and the urine fungal culture result turned negative after 10 days.Conclusion:For patients suffering from complicated infections,clinical pharmacists should fully consider the conditions of the patients to assist physicians in making more accurate judgments,so as to formulate more individualized anti-infective treatment regimens and implement pharmaceutical care,thereby ensuring the medication safety and effectiveness for patients.
infective endocarditisanti-infective therapypharmaceutical carepharmaceutical care
万方数据
维普
