摘要
小檗碱是一种具有广泛药理作用的生物活性物质,除了抗炎、抗菌、抗病毒、抗腹泻、抗高血压、抗缺氧、降血糖、降血脂等作用外,还具有抗肿瘤作用.既往已有小檗碱抗胃癌、结直肠癌、皮肤癌、胰腺癌等的相关报道,该文主要就小檗碱抗食管癌和肉瘤的药理作用及其机制进行了综述,并做了相关点评和分析.
Abstract
Berberine is a bioactive substance with a wide range of pharmacological effects.In addition to anti-inflammatory,antibacterial,antiviral,antidiarrheal,antihypertensive,antihypoxic,hypoglycemic and hypolipidemic effects,berberine also has antitumor effects.There have been reports on the effects of berberine against gastric cancer,colorectal cancer,skin cancer,pancreatic cancer,etc.The pharmacological effects and mechanisms of berberine against esophageal cancer and sarcoma are reviewed,and relevant comments and analyses are made in this article.
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