Analysis of Clinical Characteristics of Adverse Drug Reactions Related to Anti-infective Drugs in a Hospital
Objective:To analyze the clinical characteristics of adverse drug reactions(ADRs)related to anti-infective drugs in the hospital and provide reference for the clinical safe use of anti-infective drugs.Methods:The anti-infective drug related ADR reports of 107 patients reported by Anyang District Hospital of Puyang City from January 2022 to December 2023 were selected as research data.The information such as patient age,gender,type of ADR reports,type and dosage form of drugs,organs involved and clinical manifestations was collected to analyze the clinical characteristics of anti-infective drug related ADRs.Results:Among the ADR reports of 107 cases,the report type was mainly"general"(97 cases,60.65%),and the reports of"new and general"and"serious"types only involved 6 cases and 4 cases respectively.In terms of gender,the number of male patients with ADRs was slightly more than that of female patients(56 cases vs 51 cases);in terms of age,most patients were over 50 years old(71 cases,66.36%).In terms of drug types,the drugs involved in ADRs were mainly quinolones(48 cases,44.86%)and cephalosporins(20 cases,18.69%);in terms of dosage forms,the main drugs were injections(53 cases,49.53%)and powder injections(53 cases,49.53%);the main organs involved were skin and its appendages(54 cases,50.47%),followed by the gastrointestinal system(14 cases,13.08%)and injection sites(10 cases,9.35%).Conclusion:Anti-infective drug related ADRs mostly occur in the middle-aged and elderly individuals;the main drug types are quinolones and cephalosporins,and the dosage forms are basically injection preparations.Therefore,it is required to strengthen the relevant clinical monitoring to ensure the safe medication for patients.
anti-infective drugsadverse drug reactionsclinical characteristicsrational use of drugs
万方数据
维普
