Research on Antibacterial Activity of Alcohol Extracts from Different Parts of Foeniculum vulgare Mill
Objective:To compare the antibacterial activity of alcohol extracts from different parts of Foeniculum vulgare Mill.,and provide reference for further medicinal development of Foeniculum vulgare Mill.Methods:Effective components from roots,branches and leaves,and fruits of Foeniculum vulgare Mill.were extracted using 20%ethanol solution.The inhibitory zone diameters and minimal inhibitory concentrations(MIC)of alcohol extracts from roots,branches and leaves,and fruits of Foeniculum vulgare Mill.against Staphylococcus aureus,Escherichia coli,and Bacillus subtilis were measured using the filter paper disc method and microdilution method,then the antibacterial activity of alcohol extracts from different parts of Foeniculum vulgare Mill.was compared.Results:The detection results with the filter paper disc method showed that alcohol extracts from roots,branches and leaves,and fruits of Foeniculum vulgare Mill.exhibited antibacterial activity against Staphylococcus aureus,Escherichia coli,and Bacillus subtilis.The alcohol extracts from fruits of Foeniculum vulgare Mill.demonstrated the strongest antibacterial activity against Staphylococcus aureus and Escherichia coli,while the alcohol extracts from roots of Foeniculum vulgare Mill.showed the strongest antibacterial activity against Bacillus subtilis.The detection results with the microdilution method indicated that MIC values of alcohol extracts from roots,branches and leaves,and fruits of Foeniculum vulgare Mill.against Staphylococcus aureus were 5.00,10.00,and 5.00 mg/mL respectively,MIC values against Escherichia coli were 10.00 mg/mL uniformly,and MIC values against Bacillus subtilis were 20.00,20.00,and 10.00 mg/mL respectively.Conclusion:Alcohol extracts from roots,branches and leaves,and fruits of Foeniculum vulgare Mill.exhibit strong antibacterial activity against Staphylococcus aureus,Escherichia coli,and Bacillus subtilis,with the highest antibacterial effect on Staphylococcus aureus,followed by Escherichia coli,and Bacillus subtilis.
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