科技导报2024,Vol.42Issue(19) :119-127.DOI:10.3981/j.issn.1000-7857.2024.01.00113

"人民科学家"顾方舟:中国消灭脊灰的先驱者

"People's Scientist"Gu Fangzhou:A pioneer of polio eradication in China

左锟澜 黄剑良 孙博 刘欢
科技导报2024,Vol.42Issue(19) :119-127.DOI:10.3981/j.issn.1000-7857.2024.01.00113

"人民科学家"顾方舟:中国消灭脊灰的先驱者

"People's Scientist"Gu Fangzhou:A pioneer of polio eradication in China

左锟澜 1黄剑良 1孙博 2刘欢3
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作者信息

  • 1. 中国科学技术大学科技史与科技考古系,合肥 230026
  • 2. 北京中医药大学第三附属医院,北京 100029
  • 3. 中国科学技术大学科技史与科技考古系,合肥 230026;病毒学国家重点实验室,武汉 430072
  • 折叠

摘要

中国病毒学家顾方舟,是中国组织培养口服减毒疫苗的开拓者,他的研究工作极大地提高了脊灰减毒疫苗的接种效果,使千百万儿童免受脊灰的威胁.以顾方舟为研究对象,介绍了顾方舟走上公共卫生和病毒学道路的原因以及研制中国首批"脊灰"减毒疫苗的过程等,讨论了影响脊灰疫苗技术路线选择的因素,以及疫苗的生产、检定、临床试验的过程与结果.

Abstract

Gu Fangzhou's work has significantly improved the effectiveness of polio attenuated vaccine and protected millions of children from the threat of polio.As a pioneer in the development of China's oral attenuated vaccine through cell culture,Gu's journey into public health and virology is explored in this paper.The reasons behind Gu's pursuit of a career in public health and virology are introduced and the process of developing China's first batches of attenuated polio vaccines is detailed.Furthermore,the factors influencing the choice of technical routes for polio vaccine development is discussed,as well as the processes and results of vaccine production,verification,and clinical trials.Gu has closely linked his personal destiny with the future of the nation.His research and efforts have significantly improved the health and quality of life for hundreds of millions of people.

关键词

顾方舟/脊髓灰质炎/减毒疫苗/卫生健康/科技史

Key words

Gu Fangzhou/polio/attenuated vaccine/public health/history of science and technology

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基金项目

中国疾病预防控制中心项目(BB2110240080)

中国科学技术大学质量工程项目(2023XXSKC03)

中国科学技术大学质量工程项目(2023YCZX02)

出版年

2024
科技导报
中国科学技术协会

科技导报

CSTPCD北大核心
影响因子:0.559
ISSN:1000-7857
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