Multivariate statistical analysis has important application value in the practice of big data analysis,this course requires students to master a variety of statistical methods and be familiar with the operation of statistical software.In this study,in view of a series of problems in the multivariate statistical analysis course,project-based teaching is applied in practice,and the learning tool adopts case teaching,combining the online and offline learning methods of SPOC mode and the systematic course teaching mode of BOPPPS mode.It aims to enhance the ability of undergraduate students to learn and master the knowledge of multivariate statistical analysis and the ability to use statistical software tools to solve practical problems.