The integration of industry and education is an important strategic direction for promoting the coordinated development of vocational education and a strategic measure for advancing the development of modern health industries.The article explores the diversified reform of the talent training mode for nursing majors in vocational colleges,with the background of the integration of industry and education.Firstly,it is necessary to clarify the talent training objectives of vocational nursing majors and the needs and integration points of industry education under the premise of the development of the health industry.Secondly,the path direction of"three in one"is proposed,the"1+X"certificate system is implemented,and the modern apprenticeship education model is implemented,so that the overall development of talent cultivation is oriented towards"big majors and multiple directions",forming a characteristic curriculum system of"course job docking and course certificate integration",providing a broader learning and practice platform for vocational nursing students,and laying a solid foundation for providing higher quality skilled nursing talents to society.