As an emerging field that integrates biology,engineering,chemistry and information technology,synthetic biology is the frontier representative of the field of biology in the 21st century to promote disruptive innovation,and it is also a key force driving the development of the future bioeconomy.This paper analyzes and discusses the develop-ment trend of synthetic biology at home and abroad,and finds that the United States is currently in the leading posi-tion in the world,and China is still in the early stage of development,but it has outstanding advantages in basic re-search such as patent applications,and initially forms a synthetic biology development model represented by Shenzhen,Tianjin and Shanghai.Based on the development foundation of synthetic biology in Zhejiang in terms of technology re-serve,innovation platform and landmark achievements,the study analyzed the in strategic planning,innovation re-sources,innovation subjects and science and technology ethics based on comparative analysis,and proposed counter-measures and suggestions to accelerate the technological innovation and industrial development of synthetic biology and promote the high-quality development of biological economy.