Progress in Treatment of Bacterial Infections of Orthopedic with Phage Therapy
Antibiotics play an important role in treating bacterial infections.However,with the long-term ex-cessive use and misuse of antibiotic drugs,the global antibiotic resistance crisis has been caused,which brings challenges to clinical infection treatment.Due to host specificity,high bactericidal activity,and excellent bio-safety,bacteriophages become a natural antibiotic alternative antibacterial agent.Bacteriophages against multire-sistant bacteria attracted people's attention.Infection is one of the serious complications in orthopedic surgery,which causes significant increases in patient morbidity and medical costs.We aim to provide a new perspective on bacteriophage therapy in orthopedic infections by summarizing the advantages of bacteriophage therapy,the application of bacteriophage therapy in orthopedic infections,and the challenges of bacteriophage therapy.
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