Research progress on cross-dermal intercellular signaling regulation of tooth development
The cross-dermal interaction and secretion of related signaling molecules drived cell differentiation and organogenesis.From pattern formation,morphogenesis,to functional differentiation of teeth,various cross-dermal signaling molecules were involved.In recent years,with the application of novel technologies such as single-cell transcription profiling,some unique cell subpopulations and intercellular interactions have been reported,promoting further research on tooth development.This article reviews new findings in the use of single-cell transcriptome sequencing to study tooth development processes in recent years,with a focus on advances in cross-dermal intercellular signaling.
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