Hypoxia and periodontitis:occurrence,progression,and novel treatment strategies
Enhanced metabolism of periodontal tissues,microcirculatory disturbances,and proliferation of periodontal bacteria within periodontal pockets resulting in a hypoxic microenvironment are significant pathophysiological features of periodontitis.Important risk factors for the occurrence and progression of periodontitis include high-altitude residence,obstructive sleep apnea syndrome,smok-ing,which induce low oxygen levels in periodontal tissues and periodontal pockets.The interaction between hypoxia and periodontitis promotes the occurrence and development of periodontitis.This review explores the interaction between hypoxia and periodontitis,as well as the latest research progress on treatment strategies based on the hypoxic microenvironment within periodontal pockets,providing insights for the prevention and treatment of periodontitis.
万方数据
维普
