Research advances of Dnmt3b on temporomandibular joint osteoarthritis
Temporomandibular joint osteoarthritis(TMJOA)is a common disease characterized by progressive cartilage degenera-tion,subchondral bone remodeling and chronic pain.The exact pathogenesis of TMJOA is unclear.Dnmt3b is a kind of DNA methyl-transferase,which can promote the repair and regeneration of temporomandibular joint.This review summarizes the research progress of Dnmt3b in TMJOA,in order to provide a new idea for the treatment of TMJOA.
DNA methyltransferase 3btemporomandibular joint osteoarthritisepigenetic