As the foremost physiological barrier of the organism,the oral mucosa is perpetually subjected to an environment replete with microorganisms,allergens,food antigens,and high-frequency mechanical stimuli.Nevertheless,it sustains a remarkable long-term stability.The defense system of the oral mucosa assumes an indispensable role in the preservation of local and systemic immune homeo-stasis.This article reviews the research advancements regarding the composition,functions,and disease-related roles of the oral muco-sal defense system.The overarching objective is to enhance the comprehension of the etiopathogenesis underlying oral mucosal diseases and to foster the development of preventive and therapeutic strategies predicated on the oral mucosal defense system.
关键词
黏膜免疫/上皮屏障/口腔稳态/口腔黏膜防御系统
Key words
mucosal immunity/epithelial barrier/oral homeostasis/oral mucosal defense system
维普
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