The osteogenic mechanism of MXene nanomaterials in biomedical applications
MXene nanocomposites are an emerging bioactive material with good physicochemical properties and biocompatibility,and have been used in various studies on tissue engineering and regeneration.MXene nanocomposites have been found to promote the adhe-sion,proliferation and differentiation of osteogenic-related cells,regulate the expression of osteogenic-related genes and proteins,mod-ulate related signaling pathways,and promote angiogenesis at the defect site,thereby facilitating the repair of bone defects.This makes it a popular research material in bone tissue regeneration.In this paper,we review the specific mechanism of MXene nanocomposites in promoting bone regeneration to provide a theoretical basis and new ideas for its application in basic and clinical research.