Research progress of luteolin in the prevention and treatment for periodontitis
Luteolin is a natural flavonoid with four hydroxyl groups that originates from plants.It has been extensively investigated in various inflammatory disease models in recent years,and exhibits great application prospect in the prevention and treatment for peri-odontitis.However,the clinical application of luteolin in periodontitis remains unexplored,and the development potential,underlying mechanisms and safety of luteolin require further investigation.This review will provide a comprehensive overview of the effects of luteo-lin on soft tissue destruction and alveolar bone loss associated with periodontitis.
luteolinperiodontitisinflammatory responsealveolar bone resorptionmatrix metalloproteinase