Objective To provide reference for clinical selection of fluid resins by comparing the bonding properties of Beautifil Flow Plus F00,FiltekTM Z350 XT,SDR,Tetric® N-Flows and Constic with tooth enamel.Methods Fifty adult extrinsic premolars were se-lected for orthodontic extraction and randomly divided into five groups(n=10),namely F00 group,Z350 group,SDR group,Tetric group and Constic group,and each group was a parallel control group.One third of the cheek of each isolated tooth was removed by grinding the enamel with the thickness of 0.5 mm,and a circular shape with a diameter of 3 mm was used as the bonding surface.Ten cylindrical resin specimens with a diameter and length of 3 mm were prepared for bonding with the prepared tooth enamel surface,and self-coagulation resin was embedded.After 3 000 times of alternating cold and hot cycles and 24 h of constant temperature water bath at 37 ℃,the shear strength test was carried out;the data were recorded,and the cut bonding interface was observed under scanning elec-tron microscope.Results The shear strength of group F00 was(18.39±2.93)MPa,and that of group Z350 was(11.03±1.55)MPa.The shear strength of,SDR group was(12.77±1.55)MPa;Tetric group was(15.25±1.88)MPa and Constic group was(12.79±2.78)MPa.ANOVA test and SNK test were performed on the obtained data.The shear strength of F00 group was significantly higher than that of Z350 group,SDR group,Tetric group and Constic group(P<0.05).The shear strength of Tetric group was significantly higher than that of Z350 group,SDR group and Constic group(P<0.05).There was no significant difference in shear strength among Z350 group,SDR group and Constic group(P>0.05).Conclusion Among the five fluid resins,Beautifil Flow Plus F00 fluid resin has the highest bonding performance,followed by Tetric® N-Flow fluid resin,and FiltekTM Z350 XT,SDR and Constic fluid resin have low bonding performance.