New developments in the clinical presentation and diagnosis of granulomatosis with poly angiitis
Granulomatosis with polyangiitis is a systemic vasculitis disease,which can involve multiple organs of the whole body such as mouth,eyes,nose,lung and kidney.It has low incidence but a high mortality rate,hidden onset,and early symptoms are easily confused with other diseases.It is mainly characterized by the formation of granuloma,focal necrosis and vascular inflammation.The combination of glucocorticoid and immunosuppressant is usually used in clinical treatment.The diagnostic criteria of granulomatosis with polyangiitis has been reformulated with the development of modern technology and increased recognition of its clinical manifestations.Therefore,this paper mainly updated the clinical manifestations,classification diagnostic criteria and differential diagnosis of granulom-atous polyvasculitis from the perspective of oral cavity,in order to provide reference for clinical work.
granulomatosis with polyangiitisautoimmune diseaseclinical presentationdiagnosisdifferential diagnosis
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