Research progress of LncRNA-mediated miRNA regulating osteogenic differentiation of PDLSCs in microenvironment
The study on periodontal tissue regeneration can provide a possible clinical coping strategy for alveolar bone defect.As an important seed cell,periodontal stem cells play an important role in alveolar bone repair.Long non-coding RNA,as competing endoge-nous RNA,can play an important regulatory role in post-transcriptional levels.This paper reviews the mechanism of lncRN A-mediated miRNA on osteogenic differentiation of PDLSCs under physiological state,inflammatory microenvironment and mechanical stimulation.
Long non-coding RNAcompeting endogenous RNAmicroRNAperiodontal ligament stem cellsosteogenic differenti-ation
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维普
