Role of neutrophil in periodontitis:An updated review
Periodontitis is a prevalent and persisting oral inflammation,during which host factors are critically involved.As the most abundant immune cells,neutrophils actively partake in periodontal homeostasis,the alteration of neutrophil number or function could aggravate periodontitis through multifaceted mechanisms.Additionally,neutrophil-targeted therapies showed promising effects on treating periodontitis in animal trials.In this paper,research progress of neutrophil's role in periodontitis and immunomodulation on neutrophil were reviewed in order to provide new perspectives for periodontitis treatment.