首页|预防性经皮胃造瘘对口腔癌切除并同期修复重建术后术区感染影响的研究

预防性经皮胃造瘘对口腔癌切除并同期修复重建术后术区感染影响的研究

扫码查看
目的:探究不同肠内营养方式对口腔癌根治性切除术并同期行修复重建术后术区感染的影响.方法:回顾性分析2018年1月~2023年1月就诊于新疆医科大学第一附属医院口腔颌面肿瘤外科接受口腔癌根治性切除术并同期行修复重建的患者的临床资料,根据给予的不同肠内营养方式,将纳入病例分为预防性经皮胃造瘘组(n=26)、鼻饲管组(n=54)及经口进食组(n=33).比较3组患者手术治疗后术区感染率、皮瓣坏死率情况.结果:预防性经皮胃造瘘组患者术区感染率显著低于鼻饲管组和经口进食组(P<0.05);3组间皮瓣坏死率比较差异无统计学意义(P>0.05).术后6周患者体重指数、总蛋白、白蛋白、肌酐、红细胞压积值与入院时测量的差值在3组间比较存在明显差异(P<0.01).结论:预防性经皮胃造瘘可以有效降低口腔癌根治性切除术并同期行修复重建术后皮瓣感染率,值得临床推广.
Effect of Prophylactic Percutaneous Endoscopic Gastrostomy on Postoperative Infection in Oral Cancer Patients Under-went Radical Resection along with Reconstruction
Objective:To investigate the effects of different types of enteral nutrition on surgical site infection after extensive resection and simultaneous reconstruction of patients with oral cancer.Methods:The data of patients who underwent oral cancer radical resection along with reconstruction at Oncological Department of Oral and Maxillofa-cial Surgery,the First Affiliated Hospital of Xinjiang Medical University from January 2018 to January 2023 were retrospectively analyzed.According to different enteral nutrition,the patients were divided into the group of proph-ylactic percutaneous endoscopic gastrostomy(26 cases),group of nasogastric tube(54 cases),and group of oral feeding(33 cases).The changes of postoperative surgical site infection rate and flap necrosis rate among three groups were analyzed through SPSS 25.0 statistical software.Results:The postoperative surgical site infection rate in the group treated with prophylactic percutaneous endoscopic gas-trostomy was significantly lower than that in nasogastric tube group and oral feeding group(P<0.05).The rate of flap necrosis had no statistical significance among three groups(P>0.05).The difference of body mass index,total protein,albumin,creatinine,and hematocrit between admission and 6 weeks after surgery was significantly differ-ent among three groups(P<0.01).Conclusion:Prophylactic percutaneous endoscopic gastrostomy can effectively reduce the flap infection rate after extensive resection along with simultaneous reconstruction of oral cancer cases,which is worthy of clinical promotion.

oral cancerrepair and reconstructionsurgical site infectionprophylactic percutaneous endo-scopic gastrostomy

帕热克江·帕塔尔、李晨曦、克热木·阿巴司、胡露露、方昌、龚忠诚

展开 >

新疆医科大学第一附属医院(附属口腔医院)口腔颌面肿瘤外科 新疆乌鲁木齐 830054

新疆维吾尔自治区口腔医学研究所 新疆乌鲁木齐 830054

华中科技大学同济医学院附属协和医院口腔医学中心,口腔颌面发育与再生湖北省重点实验室 湖北武汉 430022

口腔癌 修复重建 术区感染 预防性经皮胃造瘘

国家自然科学基金口腔颌面发育与再生湖北省重点实验室开放基金新疆维吾尔自治区科研创新项目

823604812022kqhm008XJ2023G174

2024

口腔医学研究
武汉大学口腔医学院

口腔医学研究

CSTPCD北大核心
影响因子:0.48
ISSN:1671-7651
年,卷(期):2024.40(1)
  • 5