首页|富硒小麦草牙膏对控制牙菌斑和减轻牙龈炎效果的临床研究

富硒小麦草牙膏对控制牙菌斑和减轻牙龈炎效果的临床研究

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目的:探讨富硒小麦草牙膏减轻牙龈炎症及控制牙菌斑作用的临床效果.方法:本临床试验遵守随机、对照、双盲的设计原则,按纳入和排除标准将年龄 18~65 岁间的 72 例受试者随机分成试验组和对照组,试验组使用富硒小麦草牙膏,对照组使用不含富硒小麦草其余成分完全相同的牙膏,分别在基线、1、3 和 6 个月采用改良 Loe-Sil-ness牙龈指数、龈沟出血指数和改良 Quigley-Hein菌斑指数评价牙周状况.结果:1、3 和 6 个月时,牙龈指数试验组对照组均数计分分别为 1.16±0.10 和 1.26±0.22,0.99±0.91 和 1.21±1.16,0.92±0.11 和 1.01±0.11;龈沟出血指数试验组对照组均数计分分别为 1.12±0.23 和 1.24±0.27,1.05±0.11 和 1.13±0.15,0.91±0.12 和 1.05±0.09;牙菌斑指数试验组对照组均数计分分别为 1.37±0.20 和 1.54±0.19,1.14±0.21 和 1.37±0.24,0.98±0.16和 1.21±0.22,3 个月和 6 个月时比较,差异有统计学意义(P<0.05).说明其具有抑制牙菌斑和促进牙龈健康的作用.在本临床研究中未观察到不良反应,验证了富硒小麦草牙膏的安全性.结论:本研究提示富硒小麦草牙膏可以明显控制牙菌斑的形成,促进牙龈健康.
Clinical Study on Effect of Selenium-enriched Wheat Grass Toothpaste on Reducing Gingival Inflammation and Control-ling Dental Plaque
Objective:To investigate the clinical impact of toothpaste enriched with selenium-rich wheat grass.Methods:Following the principles of randomized,double-blind,controlled design,72 participants aged 18 to 65 years were randomly assigned to either the experimental group(using selenium-rich wheat grass toothpaste)or the control group(using no selenium-rich wheat grass toothpaste).The gingival index,gingival bleeding index,and plaque index were evaluated at baseline,1 month,3 months,and 6 months after treatment.Results:At 1,3 and 6 months,the mean scores of gingival index in experimental group and control group were 1.16±0.10 and 1.26±0.22,0.99±0.91 and 1.21±1.16,0.92±0.11 and 1.01±0.11,respectively.The mean scores of gingival sulcus bleeding index in the experimental group and control group were 1.12±0.23 and 1.24±0.27,1.05±0.11 and 1.13±0.15,0.91±0.12 and 1.05±0.09,respectively.The mean scores of plaque index in the experimental group and control group were 1.37±0.20 and 1.54±0.19,1.14±0.21 and 1.37±0.24,0.98±0.16 and 1.21±0.22,respectively.Notably,no adverse effects were observed during this clinical study.Conclusion:Selenium-enriched wheat grass toothpaste significantly hampers dental plaque formation,alleviates gingivitis,and enhances gum health.

selenium-rich wheat grass toothpastegingival inflammationdental plaque

皮小琴、朱彬、童国勇、李森森、赵国栋、张怡婷、杨再波

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恩施土家族苗族自治州中心医院口腔诊疗中心 湖北 恩施 445002

武汉大学恩施临床学院 湖北 恩施 445002

湖北医药学院 湖北 十堰 442000

富硒小麦草 牙膏 牙龈炎症 牙菌斑

2023年湖北省自然科学基金联合基金

2023AFD073

2024

口腔医学研究
武汉大学口腔医学院

口腔医学研究

CSTPCD北大核心
影响因子:0.48
ISSN:1671-7651
年,卷(期):2024.40(3)
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