口腔医学研究2024,Vol.40Issue(3) :275-278.DOI:10.13701/j.cnki.kqyxyj.2024.03.017

以口腔黏膜溃疡为首发表现的结外鼻型NK/T细胞淋巴瘤的多学科诊疗1例

Multidisciplinary Diagnosis and Treatment of Extranodal Nasal Type NK/T Cell Lymphoma with Oral Mucosal Ulcer as the First Manifestation:A Case Report

王锋 陈旭亚 周刚 张静
口腔医学研究2024,Vol.40Issue(3) :275-278.DOI:10.13701/j.cnki.kqyxyj.2024.03.017

以口腔黏膜溃疡为首发表现的结外鼻型NK/T细胞淋巴瘤的多学科诊疗1例

Multidisciplinary Diagnosis and Treatment of Extranodal Nasal Type NK/T Cell Lymphoma with Oral Mucosal Ulcer as the First Manifestation:A Case Report

王锋 1陈旭亚 1周刚 1张静1
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作者信息

  • 1. 口颌系统重建与再生全国重点实验室,口腔生物医学教育部重点实验室,口腔医学湖北省重点实验室,武汉大学口腔医(学)院口腔黏膜科 湖北 武汉 430079
  • 折叠

摘要

结外鼻型NK/T 细胞淋巴瘤(extranodal nasal type NK/T-cell lymphoma,ENKTL)是一种以破坏面部中份结构为主的 NK/T细胞来源的非霍奇金淋巴瘤,临床少见.以口腔黏膜溃疡为首发症状的病例罕见且易与其他疾病相混淆,在诊断上极其困难.本文报道 1 例以颊黏膜及牙龈溃疡为首发表现的 ENKTL 的多学科诊疗,并分析该疾病的临床病理学特征、诊断、鉴别诊断和治疗,以期为临床诊治相关病例提供参考.

Abstract

Extranodal NK/T cell lymphoma,nasal type(ENKTL),is a rare and unique non-Hodgkin's lymphoma that primarily affects the middle face and originates from T cells or NK cells.It is uncommon for cases to present with an oral ulcer as the initial symptom,which can lead to confusion with other diseases and pose challenges for di-agnosis.This paper presents a case study on the diagnosis and treatment of Extranodal NK/T-cell lymphoma,nasal type(ENKTL)with initial symptoms of buccal mucosa and gingival ulcer.It analyzes the clinicopathological charac-teristics,diagnosis,differential diagnosis,and treatment of the disease to offer guidance for clinical management of similar cases.

关键词

结外鼻型NK/T细胞淋巴瘤/口腔黏膜溃疡/多学科诊疗

Key words

extranodal NK/T cell lymphoma/oral ulcer/multidisciplinary diagnosis and treatment

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基金项目

国家自然科学基金(82170965)

出版年

2024
口腔医学研究
武汉大学口腔医学院

口腔医学研究

CSTPCDCSCD北大核心
影响因子:0.48
ISSN:1671-7651
参考文献量20
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