首页|预防性根尖封闭后自体移植牙的临床和根尖周愈合评估

预防性根尖封闭后自体移植牙的临床和根尖周愈合评估

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目的:探究预防性根尖封闭对自体移植牙的根尖周愈合的影响.方法:3条比格犬随机纳入24颗前牙,分对照组、RCT组(术中根管治疗)、Ref组(术中截根,倒封闭根尖),n=8.移植术后1、4、12周评估移植牙松动、脱落数和影像学指标;术前、术后4、12周记录探诊深度.12周后,对样本进行Micro CT扫描[计算骨体积分数比值(bone volume/tissue volume,BV/TV)、骨小梁分离度(trabecular separation,Tb.Sp)、骨小梁数目(trabecular num-ber,Tb.N)、骨小梁厚度(trabecular thickness,Tb.Th)]和苏木精-伊红(hematoxylin-eosin,HE)染色.对量化松动度、探诊深度(probing depth,PD)值和Micro CT结果进行分析统计.结果:对照组和Ref组脱落2颗牙,RCT组脱落1颗,平均松动度受时间和分组影响显著(P<0.05).PD值的下降与时间显著相关(P<0.05),RCT组和Ref组显著低于对照组;X线片中,牙槽骨高度随骨改建逐渐降低,对照组部分牙根出现外吸收.RCT组的Tb.Sp明显低于对照组(P<0.05).对照组的Tb.N明显低于其他两组(P<0.05,P<0.01);RCT组和对照组牙根表面见浅表性吸收,Ref组的根尖组织致密,牙周层次清晰;RCT组根尖组织排列疏松.结论:预防性根尖封闭在自体移植牙中具有效性,可简化术后治疗,促进自体移植牙周骨重建,因此是对自体植牙术的有效改良.
Clinical and Periapical Healing Assessment of Autograft Teeth after Prophylactic Apical Closure
Objective:To evaluate the effect of apical surgery on autotransplantation teeth from three perspectives:clinic,image,and histology.Methods:Twenty-four teeth of three beagle dogs were randomly divided into a control group,an RCT group,and a Ref group(transplantation after root-end filling treatment).Clinical and image exami-nations were performed at 1,4,and 12 weeks after surgery.Samples were subjected to micro CT scanning(calcu-lated BV/TV,Tb.Sp,Tb.N,Tb.Th)and HE staining.Analytical statistics were performed to quantify loose-ning,PD values,and micro CT results.Results:Several teeth were lost in the three groups,and there was an im-provement in the looseness at 12 weeks postoperatively.Mean loosening was significantly influenced by time and group(P<0.05).The decrease in PD values was significantly associated with time(P<0.05)and was significant-ly lower in the RCT and ref groups than that in the control group.In X-ray films,alveolar bone height was gradual-ly decreased with bone remodeling,and some roots in the control group showed external resorption.The Tb.Sp in the RCT group was significantly lower than that in the control group(P<0.05).The Tb.N in the control group was significantly lower than those in the other two groups(P<0.05 and P<0.01).The apices of the Ref group were more closely related to the physiological structure and exhib-ited active bone repair confirmed by histology.Conclusion:Prophylactic apical sealing is effective in autograft teeth,which can simplify postoperative treatment and promote per-iodontal bone reconstruction of doner teeth.Accordingly,it is an effective modification of RCT for autografted teeth.

autotransplantated teethroot-end fillingiRoot Bp plusperiodontal healingapical healing

陈月、池峻舟、刘娟秀、任小华、田鲲

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西南医科大学附属口腔医院 四川 泸州 646000

四川省医学科学院·四川省人民医院口腔科(电子科技大学附属医院)四川成都 610072

自体移植牙 预防性根尖封闭 iRoot Bp plus 牙周愈合 根尖愈合

口腔移植工程四川省青年科技创新研究团队项目电子科技大学-四川省人民医院"医工交叉联合基金"项目

2021JDTD0005ZYGX2021YGLH0XX

2024

口腔医学研究
武汉大学口腔医学院

口腔医学研究

CSTPCD北大核心
影响因子:0.48
ISSN:1671-7651
年,卷(期):2024.40(6)
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