首页|以黏膜皮肤色素沉着为首发表现的艾迪生病1例

以黏膜皮肤色素沉着为首发表现的艾迪生病1例

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原发性肾上腺皮质功能减退症,又称艾迪生病,是一种罕见的、与自身免疫密切相关的肾上腺疾病,可伴发黏膜皮肤色素沉着等各类全身表现,甚至发生肾上腺危象而危及生命.口腔黏膜色素沉着常早于皮肤出现,易与其他色素沉着类疾病相混淆,在临床中易被误诊.本文报道了 1例以黏膜皮肤色素沉着为首发表现的艾迪生病,及时诊治后口腔黏膜和皮肤色素沉着完全消失,为该病提供了具有口腔黏膜专科特色的诊疗思路.
A Case of Addison's Disease with Mucosal Skin Pigmentation as Initial Manifestation
Primary adrenal insufficiency,also known as Addisons disease,is a rare adrenal diseases closely related to autoimmune diseases that can be accompanied by various systemic manifestations,including mucosal and skin pigmentation,and even lead to adrenal crisis that endangers life.Pigmentation of oral mucosa often appears earlier than on the skin,which may be confused with other pigmentation related diseases and easily misdiagnosed in clinical practice.This article reports a case of Addison's disease with mucosal and skin pigmentation as the initial symptom.After timely diagnosis and treatment,the pigmentation completely disappeared,providing a specialty diagnosis and treatment approach with oral mucosal characteristics for this disease.

Addison's diseasePrimary adrenal insufficiencypigmentation

陈潇婕、卢锐、周刚

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口颌系统重建与再生全国重点实验室,口腔生物医学教育部重点实验室,口腔医学湖北省重点实验室,武汉大学口腔医院口腔黏膜科 湖北 武汉 430079

艾迪生病 原发性肾上腺皮质功能减退症 色素沉着

2024

口腔医学研究
武汉大学口腔医学院

口腔医学研究

CSTPCD北大核心
影响因子:0.48
ISSN:1671-7651
年,卷(期):2024.40(9)