目的:通过与化脓性颌骨骨髓炎进行对比,总结药物相关性颌骨坏死(medication-related osteonecrosis of thejaw,MRONJ)的影像学及临床特点.方法:回顾性分析MRONJ与化脓性颌骨骨髓炎患者的影像学和临床资料.结果:MRONJ病例中:100％(对比化脓性颌骨骨髓炎的14.0％)见骨硬化,30.8％(对比5.0％)见多象限骨硬化,43.6％(对比4.0％)见死骨,25.6％(对比0％)见死骨伴多象限骨硬化;89.7％(对比20.0％)诱因是拔牙.结论:相较于化脓性颌骨骨髓炎,MRONJ观察到骨硬化、多象限骨硬化和死骨影像表现的概率更高,多象限骨硬化伴死骨影像出现时提示其很可能是MRONJ;拔牙是MRONJ的最主要诱因.
Abstract
Objective:To summerize the imaging and clinical features of MRONJ(medication-related osteonecrosis of the jaw)by comparing with suppurative osteomyelitis of the jaw.Methods:The imaging and clinical data of patients with MRONJ were retrospectively analyzed with those of patients with suppurative osteomyelitis of the jaw.Results:In the cases of MRONJ,100％(compared to 14.0％of suppurative osteomyelitis of the jaw)were observed with osteosclerosis,30.8％(compared to 5.0％)were observed with multiquadrant osteosclerosis,43.6％(compared to 4.0％)were observed with sequestrum,25.6％(compared to 0％)were observed with sequestrum and multiquadrant osteosclerosis,and 89.7％(compared to 20.0％)of the inducements were tooth extraction.Conclusion:Compared to suppurative osteomyelitis of the jaw,the probability of oberving osteosclero-sis,multiquadrant osteosclerosis,and sequestrum on MRONJ are higher,and when multiquadrant osteosclerosis and sequestrum appear simultaneously,it is very likely to be MRONJ.Tooth extraction is the most major induce-ment of MRONJ.
关键词
药物相关性颌骨坏死/双膦酸盐/影像学特点/死骨/骨质硬化
Key words
medication-related osteonecrosis of the jaw/biphosphonate/imagigng feature/sequestrum/osteosclerosis
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