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大气中黑碳的暴露及人体健康效应研究进展

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空气污染暴露是人类早亡的重要风险因素,黑碳作为大气颗粒污染物的重要组分,因具有显著的健康影响受到广泛关注.我国大气中黑碳污染情况较为严重,人为源黑碳排放总量和暴露水平全球最高.最新研究表明,黑碳因其特有的物化属性可能具有比细颗粒物更大的健康影响.为加强对黑碳健康效应的认识,本文从流行病学研究的方法、暴露评估、健康结局等角度介绍国内外最新的研究进展,重点关注黑碳对呼吸系统、心血管系统和神经系统的影响.与黑碳相关的健康危害包括但不限于肺功能下降、呼吸系统炎症、血压升高、动脉粥样硬化、认知和视觉功能下降等多种问题.最新研究发现黑碳在妊娠期间的暴露可能对母体和后代造成特殊的健康危害.虽然已有的流行病学研究采取了丰富的方法并得到了相对一致的结论,关于黑碳的健康效应仍有很大不确定性.我们建议对大气中黑碳浓度开展常规的监测工作,为更全面和深入研究黑碳的健康效应和制定控制政策提供必要的证据.
A review of advances in black carbon exposure assessment and health effects
Air pollution exposure is a critical risk factor for global premature mortality,with 60%of air pollution related deaths attributed to atmospheric particles.Black carbon(BC),a crucial component of atmospheric particles,is known as a contributor to climate change because of its light absorption properties.It is primarily formed from the incomplete combustion of fossil fuels and biomass,with transportation acting as a major source in urban areas.China currently faces the highest anthropogenic emissions and exposure levels of BC in the world.In recent years,BC has garnered widespread attention due to its adverse health effects and global warming potential.Recent research suggests that BC may have more significant health effects than other components in fine particles(PM2.5,particulate matter with aerodynamic diameter≤2.5 μm)due to its unique physical and chemical properties.The large specific surface area of BC enables the absorption of toxic and hazardous substances such as polycyclic aromatic hydrocarbons and dioxins,enhancing its redox activity and toxicity.However,the extent of the health effects of BC appears inconsistent within the literature and studies suffer from inaccurate assessment of exposure,measurement errors,and limited intervention focused studies.Given the health implications of BC and the existing knowledge gap,it is necessary to summarize previous epidemiological studies in order to advance the scientific understanding of the health implications of BC.This study reviews 37 papers published in SCI journals since 2005.Other relevant findings in Chinese and English literature are included.The objective is to present an up-to-date overview of the research on the health effects of BC by reviewing a diverse range of study designs,exposure assessment methods,and epidemiological studies conducted both domestically and internationally.The spatial and temporal variation of anthropogenic BC emissions is large because of its complicated emission sources and meteorological conditions.Current epidemiological investigations primarily employ modeling techniques such as land use regression and spatio-temporal interpolation to estimate long-term exposure levels of BC.For short-term exposure assessments,offline filter sampling and online BC monitors are frequently employed.Inaccurate assessment of exposure results in inaccuracies in current epidemiological studies.In terms of adverse health effects of BC,most studies focus on the respiratory,cardiovascular,and nervous systems.The health effects associated with BC encompass a wide range of issues,including decreased lung function,respiratory inflammation,elevated blood pressure,atherosclerosis,cognitive impairment,visual decline,as well as other adverse outcomes.Additionally,BC exposure demonstrates significant associations with increased hospital admissions,emergency department visits,and deaths related to various diseases.Recent investigations have also revealed that BC inhaled during pregnancy could cross the placental barrier,resulting in health effects such as gestational diabetes for the mother and low birthweight for the child.Studies have revealed significant associations between BC exposure and adverse health effects across the reviewed literature.While numerous epidemiological studies have been conducted with relatively consistent findings,substantial uncertainty remains regarding the health effects of BC.We advocate for a requirement of routine monitoring of atmospheric BC concentrations and an increase in intervention focused studies,not only to advance investigations into the effects of BC on health,but ultimately to facilitate the development of effective control policies.Such endeavors will provide essential evidence for more comprehensive and in-depth investigations into the dual impacts of BC on climate change and human health.

black carbonexposure assessmentepidemiologyenvironmental healthair pollution

董千里、孟鑫、宫继成、朱彤

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北京大学环境科学与工程学院,北京 100871

黑碳 暴露评价 流行病学 环境健康 空气污染

国家重点研发计划国家自然科学基金

2022YFC370260092144000

2024

科学通报
中国科学院国家自然科学基金委员会

科学通报

CSTPCD北大核心
影响因子:1.269
ISSN:0023-074X
年,卷(期):2024.69(6)
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