Role of amygdala in the regulation of anxiety-like sleep disorders
Anxiety and sleep disorder are related to each other in a bidirectional way;generally,sleep disor-ders cause anxiety and people suffering from anxiety disorders experience insomnia and sleep fragmentation.The basolateral and central amygdala project to the nuclei involved in the regulation of sleep-wake states,thus playing a key role in regulating anxiety-like behavior and sleep disturbance.In this review,we summarized the anatomic structure and fiber connections of amygdalae,and their mechanisms and neural circuits that act on anxiety-like behavior and sleep disturbance so as to provide new insight into the interaction between anxiety and sleep,and come up with fundamental theories for anxiety and sleep disorder treatment.
anxietysleep-wake stateamygdalasleep disorderrapid eye movement sleepnon-rapid eye movement sleep
国家科技期刊平台
NSTL
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