Research progress of serological indicators related to portal hypertension in cirrhosis
Portal hypertension(PH)is a group of clinical syndromes,the most common cause of which is cir-rhosis.Its occurrence is closely related to liver fibrosis,intrahepatic blood flow resistance and angiogenesis.When liver cirrhosis portal hypertension occurs,some inflammatory mediators,vasoactive substances and oth-er serological indicators change during PH in cirrhosis.In recent years,these indicators have gradually been used as serological markers for non-invasive diagnosis of PH,which can predict the occurrence and develop-ment of portal hypertension and liver cirrhosis complications.Therefore,this article reviews the research prog-ress on serological indicators of portal hypertension in liver cirrhosis.
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