肝硬化门静脉高压相关血清学指标研究进展
Research progress of serological indicators related to portal hypertension in cirrhosis
蒋彤 1邓悦 1陈灵 1文皓 2石国庆1
作者信息
- 1. 遵义医科大学附属医院 消化内科,贵州 遵义 563000
- 2. 遵义医科大学第五附属(珠海)医院消化内科,广东 珠海 519100
- 折叠
摘要
门静脉高压(PH)是最常见的由肝硬化引起的一组临床综合征,其发生与肝纤维化、肝内血流阻力及血管生成等密切相关.肝硬化PH时,一些炎症介质、血管活性物质等血清学指标发生变化.近年来,这些指标逐渐被作为PH无创诊断的血清学标志物,可预测PH及肝硬化并发症的发生、发展.因此,本文就肝硬化PH相关血清学指标研究进展进行综述.
Abstract
Portal hypertension(PH)is a group of clinical syndromes,the most common cause of which is cir-rhosis.Its occurrence is closely related to liver fibrosis,intrahepatic blood flow resistance and angiogenesis.When liver cirrhosis portal hypertension occurs,some inflammatory mediators,vasoactive substances and oth-er serological indicators change during PH in cirrhosis.In recent years,these indicators have gradually been used as serological markers for non-invasive diagnosis of PH,which can predict the occurrence and develop-ment of portal hypertension and liver cirrhosis complications.Therefore,this article reviews the research prog-ress on serological indicators of portal hypertension in liver cirrhosis.
关键词
肝硬化/门静脉高压/血清学/无创诊断Key words
liver cirrhosis/portal hypertension/serology/non-invasive diagnosis引用本文复制引用
基金项目
贵州省科技计划(黔科合成果20204Y004)
省部共建协同创新中心项目(教科技厅函202039号)
出版年
2024
国家科技期刊平台
NSTL
万方数据