Research progress of maintenance therapy in acute myeloid leukemia
Acute myeloid leukemia(AML)is the most common acute leukemia in adults and usually has a poor prognosis.After intensive consolidation therapy and hematopoietic stem cell transplantation,relapse remained the most common cause of treatment failure and death and the most significant challenge to treatment.Emerging evidence has demonstrated that maintenance therapy,including hypomethylating agents,targeted drugs,and immunotherapy regimens,could prolong the duration of remission and improve survival in AML patients.This review summarized the latest and representative maintenance treatment approaches and discussed the limitations and shortcomings of current studies in order to provide theoretical support for future research and treatment.
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