Correlation between developmental dysplasia of the hip with bone mineral density and vitamin D in infants
Objective To investigate whether calcium and vitamin D deficiency in infants have any effect on hip development,in order to further the correct understanding of developmental dysplasia of the hip(DDH)among maternity women and their families,reduce the incidence of DDH and improve population quality.Methods 1 107 infants aged 3 months who underwent physical examination at the Child Health Department of Lanzhou Maternal and Child Health Hospital between March 2021 and March 2023 were first clinically examined to record the external morphology,development and movement status of the hip joint,then ultraso-nographically,and hip development was assessed by the Graf method.The infants'bone mineral density elated parameters,bone alkaline phosphatase and 25-hydroxyvitamin D[25-(OH)-D]levels were also measured to investigate whether the infants'bone mineral density and vitamin D content had any effect on the develop-ment of the hip joint via correlation analysis and multifactor logistic regression analysis.Results Among 1 107 infants examined,there were 990 cases of normal hip development and 117 of unilateral or bilateral hip dysplasia,and the detection rate of DDH was 10.6%;the left and right α angles of the DDH group were small-er than those of the normal group,and the differences were statistically significant(P<0.05);differences be-tween the left and right β angles between the two groups were not statistically significant(P>0.05);There was no linear correlation between bilateral α-angle and β-angle and bone mineral density,speed of ultrasound(SOS),z-value and 25-(OH)-D(P>0.05);bone mineral density,speed of ultrasound,z-value and 25-(OH)-D were lower in the DDH group than in the normal group,and the difference was statistically significant(P<0.05);increased bone mineral density and 25-(OH)-D were protective factors for the development of DDH.Conclusion Supplementation with appropriate calcium and vitamin D in infancy can help reduce the inci-dence of DDH.
developmental dysplasia of the hipbone mineral density25-hydroxyvitamin Dspeed of ultra-sound
万方数据
维普
