胎儿超声心动图诊断自身抗体相关的先天性心脏传导阻滞的研究进展
Research progress on fetal echocardiographic diagnosis of autoantibody-associated congenital heart block
高义朋 1邓又斌1
作者信息
- 1. 430030 武汉市,华中科技大学同济医学院附属同济医院超声影像科
- 折叠
摘要
自身抗体相关的先天性心脏传导阻滞与母体抗干燥综合征抗原A、抗干燥综合征抗原B抗体阳性均相关,该病病情进展迅速,严重的房室传导阻滞患儿死亡率较高,大多患儿需植入永久起搏器,早期准确诊断对改善患儿预后具有重要的临床意义.本文就自身抗体对心脏的影响、自身抗体相关的先天性心脏传导阻滞发病特点和胎儿超声心动图诊断的研究进展进行综述.
Abstract
Autoantibody-associated congenital heart block is associated with maternal positivity for Sjögren's syndrome antigen A and Sjögren's syndrome antigen B antibodies.The disease progresses rapidly,and the children with severe atrioventricular block have a higher mortality rate.Most affected infants require permanent pacemaker implantation,and early diagnosis is of great importance for improving fetal prognosis.This article reviews the effects of autoantibodies on the heart and conduction system,the characteristics of autoantibody-associated congenital heart block as well as the research progress on fetal echocardiographic diagnosis.
关键词
超声心动描记术/胎儿/先天性心脏传导阻滞/抗干燥综合征抗原A抗体/抗干燥综合征抗原B抗体Key words
Echocardiography/Fetus/Congenital heart block/Sjögren's syndrome antigen A antibodies/Sjögren's syndrome antigen B antibodies引用本文复制引用
出版年
2024
NETL
NSTL
维普
万方数据