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超声引导下微波消融治疗腮腺良性肿瘤的临床价值

Clinical value of ultrasound-guided microwave ablation in the treatment of benign parotid tumors

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目的 探讨超声引导下微波消融(MWA)治疗腮腺良性肿瘤的临床价值.方法 选取行超声引导下MWA治疗的18例腮腺良性肿瘤患者,比较MWA术后1、3、6、12个月肿瘤最大径、体积、体积缩小率及美容评分(CS)情况,并评估其治疗效果及与MWA相关的并发症;同时根据肿瘤的初始最大径分为≤2 cm、2~4 cm及>4cm3个亚组,比较各亚组MWA术前、后CS情况.结果 所有患者均成功治疗,随访期间均无复发.所有患者均于MWA术后出现面部轻度水肿,1例患者出现短暂性面神经损伤.MWA术后1、3、6、12个月腮腺肿瘤最大径分别为(2.56±1.49)cm、(2.26±1.26)cm、(1.67±1.05)cm、(1.47±1.01)cm;体积分别为2.68(0.87,6.16)cm3、1.86(0.57,4.46)cm3、1.15(0.19,1.91)cm3、0.74(0.09,1.28)cm3;体积缩小率分别为 37.20%±11.54%、57.48%±9.75%、81.20%±8.54%、90.01%±6.75%;患者CS分别为(2.83±0.79)分、(2.33±0.91)分、(1.89±0.90)分、(1.75±0.93)分;其中,MWA术后6、12个月腮腺肿瘤最大径和体积均较术前明显减小,MWA术后3、6、12个月体积缩小率均较MWA术后1个月明显减小,MWA术后3、6、12个月患者CS均较术前明显减小,差异均有统计学意义(均P<0.05).亚组分析显示,≤2 cm组MWA术后1、3、6、12个月CS,以及2~4 cm组MWA术后3、6、12个月CS均较术前明显减小,差异均有统计学意义(均P<0.05);各亚组间同一时间CS比较差异均有统计学意义(均P<0.05).结论 超声引导下MWA治疗腮腺良性肿瘤具有良好的临床疗效,且初始最大径较小的肿瘤术后CS减小更快,对患者进行早期干预可以获得更好的美容效果.
Objective To explore the clinical value of ultrasound-guided microwave ablation(MWA)in the treatment of benign parotid tumors.Methods A total of 18 patients with benign parotid tumors who were treated with ultrasound-guided MWA were selected,the tumor maximum diameter,tumor volume,volume reduction rate and cosmetic score(CS)at 1,3,6 and 12 months after MWA were compared,and the therapeutic effect and complications related to MWA were analyzed.At the same time,according to the initial maximum diameter of the tumor,they were divided into 3 subgroups:≤2 cm,2~4 cm and>4 cm,and the changes in CS before and after MWA were compared among the subgroups.Results All patients were successfully treated,and there was no recurrence during the follow-up.All patients experienced mild facial edema after MWA,and 1 patient experienced transient facial nerve injury.The maximum diameter of parotid tumors at 1,3,6 and 12 months after MWA were(2.56±1.49)cm,(2.26±1.26)cm,(1.67±1.05)cm and(1.47±1.01)cm,respectively.The volume were 2.68(0.87,6.16)cm3,1.86(0.57,4.46)cm3,1.15(0.19,1.91)cm3 and 0.74(0.09,1.28)cm3,respectively.The volume reduction rate were 37.20%±11.54%,57.48%±9.75%,81.20%±8.54%and 90.01%±6.75%,respectively.The CS were(2.83±0.79)points,(2.33±0.91)points,(1.89±0.90)points and(1.75±0.93)points,respectively.Among them,the maximum diameter and volume of parotid tumors were significantly reduced at 6 and 12 months after MWA compared with those before MWA.The volume reduction rate at 3,6 and 12 months after MWA was significantly reduced compared with that at 1 month after MWA.The CS at 3,6 and 12 months after MWA were significantly reduced compared with that before MWA,with statistical significance(all P<0.05).Subgroup analysis showed that compared with pre-operation,the CS of patients with the initial maximum diameter of≤2 cm at 1,3,6 and 12 months after MWA,as well as the group with the initial maximum diameter of 2~4 cm at 3,6 and 12 months after MWA were significantly reduced,with statistical significance(all P<0.05).The differences between each subgroup at the same time point were statistically significant(all P<0.05).Conclusion Ultrasound-guided MWA in the treatment of benign parotid tumors has good clinical therapeutic effects,and the tumors with a smaller initial maximum diameter have a faster postoperative CS reduction,and early intervention for patients can achieve better cosmetic results.

UltrasonographyMicrowave ablationParotid tumors,benign

庄敏、岳文胜、王诗诗、魏婷、王璐、邹杰、何怡、卢漫

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637000 四川省南充市,川北医学院医学影像学院

四川省肿瘤临床医学研究中心四川省肿瘤医院·研究所四川省癌症防治中心电子科技大学附属肿瘤医院超声医学中心

超声引导 微波消融 腮腺肿瘤,良性

国家重点研发计划国家自然科学基金

2019YFE019670082272015

2024

临床超声医学杂志
重庆医科大学第二临床学院,重庆医科大学附属第二医院

临床超声医学杂志

CSTPCD
影响因子:0.845
ISSN:1008-6978
年,卷(期):2024.26(5)