Objective To explore the clinical value of ultrasound-guided microwave ablation(MWA)in the treatment of benign parotid tumors.Methods A total of 18 patients with benign parotid tumors who were treated with ultrasound-guided MWA were selected,the tumor maximum diameter,tumor volume,volume reduction rate and cosmetic score(CS)at 1,3,6 and 12 months after MWA were compared,and the therapeutic effect and complications related to MWA were analyzed.At the same time,according to the initial maximum diameter of the tumor,they were divided into 3 subgroups:≤2 cm,2~4 cm and>4 cm,and the changes in CS before and after MWA were compared among the subgroups.Results All patients were successfully treated,and there was no recurrence during the follow-up.All patients experienced mild facial edema after MWA,and 1 patient experienced transient facial nerve injury.The maximum diameter of parotid tumors at 1,3,6 and 12 months after MWA were(2.56±1.49)cm,(2.26±1.26)cm,(1.67±1.05)cm and(1.47±1.01)cm,respectively.The volume were 2.68(0.87,6.16)cm3,1.86(0.57,4.46)cm3,1.15(0.19,1.91)cm3 and 0.74(0.09,1.28)cm3,respectively.The volume reduction rate were 37.20%±11.54%,57.48%±9.75%,81.20%±8.54%and 90.01%±6.75%,respectively.The CS were(2.83±0.79)points,(2.33±0.91)points,(1.89±0.90)points and(1.75±0.93)points,respectively.Among them,the maximum diameter and volume of parotid tumors were significantly reduced at 6 and 12 months after MWA compared with those before MWA.The volume reduction rate at 3,6 and 12 months after MWA was significantly reduced compared with that at 1 month after MWA.The CS at 3,6 and 12 months after MWA were significantly reduced compared with that before MWA,with statistical significance(all P<0.05).Subgroup analysis showed that compared with pre-operation,the CS of patients with the initial maximum diameter of≤2 cm at 1,3,6 and 12 months after MWA,as well as the group with the initial maximum diameter of 2~4 cm at 3,6 and 12 months after MWA were significantly reduced,with statistical significance(all P<0.05).The differences between each subgroup at the same time point were statistically significant(all P<0.05).Conclusion Ultrasound-guided MWA in the treatment of benign parotid tumors has good clinical therapeutic effects,and the tumors with a smaller initial maximum diameter have a faster postoperative CS reduction,and early intervention for patients can achieve better cosmetic results.