Objective To analyze and summarize the ultrasonic features of liposarcoma.Methods The ultrasonic datas of 31 patients with surgical pathologically confirmed liposarcoma in our hospital were retrospectively analyzed,and the ultrasonographic features of different pathological subtypes of liposarcoma were analyzed.Results Among the 31 patients,there were 13 cases of dedifferentiated liposarcoma,10 cases of well-differentiated liposarcoma,4 cases of pleomorphic liposarcoma,and 4 cases of myxoid liposarcoma.The maximum diameter of the tumors was(16.97±9.70)cm.The lesions were predominantly iso-hyper-echoic(61.3%,19/31),with heterogeneous echo distribution(90.3%,28/31).CDFI mostly showed lack of blood supply,and Adler blood flow classification was mainly grade 0 and grade Ⅰ(96.8%,30/31).Among them,well-differentiated liposarcoma was mainly hyperechoic(70.0%,7/10).Poorly defined boundaries of dedifferentiated liposarcoma were observed in 92.3%(12/13),and the lesions showed the biphasic pattern of hypoechoic in 46.2%(6/13)and hyperechoic in 30.8%(4/13).Pleomorphic liposarcoma was mostly characterized by a well-defined mass(3/4).The manifestations of CDFI in myxoid liposarcoma were extreme lack of blood supply(4/4).Conclusion The ultrasonic manifestations of liposarcoma have certain characteristics,which can provide some help for the clinical diagnosis of the disease.