Objective To systematically evaulate the clinical value of ultrasound ovarian-adnexal reporting and data system(O-RADS)for benign and malignant ovarian tumors.Methods A systematic search was conducted on the Cochrane Library,Embase,Web of Science and Pubmed databases for relevant literature related to the differential diagnosis of benign and malignant ovarian tumors by O-RADS from inception to September 19,2023.3 researchers independently screened the literature and extracted data,then assessed the quality of the included literature by QUADAS-2 scales.Stata 17.0,Meta-Disc 1.4 and RevMan 5.3 were used for Meta analysis.Results In this study,18 articles were reviewed,involving 10 944 patients with a total of 11 189 tumors.Meta analysis showed that the pooled sensitivity,specificity,positive likelihood ratio,negative likelihood ratio,diagnostic score and diagnostic odds ratio of O-RADS in the differential diagnosis of benign and malignant ovarian tumors were 0.95(95%CI:0.93~0.98),0.79(95%CI:0.73~0.84),4.59(95%CI:3.57~5.90),0.05(95%CI:0.03~0.09),4.52(95%CI:3.91~5.13)and 91.79(95%CI:49.79~169.27),respectively.Summary receiver operating characteristic curve analysis showed that the area under the curve of O-RADS in the differential diagnosis of benign and malignant ovarian tumors was 0.94(95%CI:0.92~0.96).Conclusion O-RADS has a good clinical value in the differential diagnosis of benign and malignant ovarian tumors.
UltrasonograhyOvarian-adnexal reporting and data systemOvarian tumors,benign and malignantMeta analysis