首页|超声卵巢-附件影像报告和数据系统鉴别诊断卵巢肿瘤良恶性的Meta分析

超声卵巢-附件影像报告和数据系统鉴别诊断卵巢肿瘤良恶性的Meta分析

Ultrasound O-RADS in the differential diagnosis of benign and malignant ovarian tumors:a systematic review and Meta-analysis

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目的 系统评价超声卵巢-附件影像报告和数据系统(O-RADS)鉴别诊断卵巢肿瘤良恶性的临床价值.方法 计算机检索Cochrane Library、Embase、Web of Science及Pubmed数据库,搜索O-RADS鉴别诊断卵巢肿瘤良恶性的相关文献,检索时间均为建库至2023年9月19日.由3名研究者独立筛查文献、提取资料,然后利用QUADAS-2量表对纳入文献质量进行评价;应用Stata 17.0、Meta-Disc 1.4及RevMan 5.3软件进行Meta分析.结果 最终纳入18篇文献,包括10 944例患者,共计11 189个肿瘤.Meta分析结果显示,O-RADS鉴别诊断卵巢肿瘤良恶性的合并灵敏度、特异度、阳性似然比、阴性似然比、诊断得分及诊断比值比分别为0.95[95%可信区间(CI):0.93~0.98]、0.79(95%CI:0.73~0.84)、4.59(95%CI:3.57~5.89)、0.05(95%CI:0.03~0.09)、4.52(95%CI:3.91~5.13)及91.79(95%CI:49.79~169.27);综合受试者工作特征曲线分析显示,O-RADS鉴别诊断卵巢肿瘤良恶性的曲线下面积为0.94(95%CI:0.92~0.96).结论 O-RADS在鉴别诊断卵巢肿瘤良恶性方面具有较好的临床应用价值.
Objective To systematically evaulate the clinical value of ultrasound ovarian-adnexal reporting and data system(O-RADS)for benign and malignant ovarian tumors.Methods A systematic search was conducted on the Cochrane Library,Embase,Web of Science and Pubmed databases for relevant literature related to the differential diagnosis of benign and malignant ovarian tumors by O-RADS from inception to September 19,2023.3 researchers independently screened the literature and extracted data,then assessed the quality of the included literature by QUADAS-2 scales.Stata 17.0,Meta-Disc 1.4 and RevMan 5.3 were used for Meta analysis.Results In this study,18 articles were reviewed,involving 10 944 patients with a total of 11 189 tumors.Meta analysis showed that the pooled sensitivity,specificity,positive likelihood ratio,negative likelihood ratio,diagnostic score and diagnostic odds ratio of O-RADS in the differential diagnosis of benign and malignant ovarian tumors were 0.95(95%CI:0.93~0.98),0.79(95%CI:0.73~0.84),4.59(95%CI:3.57~5.90),0.05(95%CI:0.03~0.09),4.52(95%CI:3.91~5.13)and 91.79(95%CI:49.79~169.27),respectively.Summary receiver operating characteristic curve analysis showed that the area under the curve of O-RADS in the differential diagnosis of benign and malignant ovarian tumors was 0.94(95%CI:0.92~0.96).Conclusion O-RADS has a good clinical value in the differential diagnosis of benign and malignant ovarian tumors.

UltrasonograhyOvarian-adnexal reporting and data systemOvarian tumors,benign and malignantMeta analysis

王潇涵、刘晶晶、杨栋梁、王春丽

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067000 河北省承德市,承德医学院

沧州医学高等专科学校

沧州市人民医院超声科

超声检查 卵巢-附件影像报告和数据系统 卵巢肿瘤,良恶性 Meta分析

2024

临床超声医学杂志
重庆医科大学第二临床学院,重庆医科大学附属第二医院

临床超声医学杂志

CSTPCD
影响因子:0.845
ISSN:1008-6978
年,卷(期):2024.26(5)