Objective To explore the clinical application value of CDFI,superb microvascular imaging(SMI)and contrast-enhanced ultrasound(CEUS)in the differential diagnosis of benign and malignant renal solid masses.Methods Totally 59 patients with renal solid masses confirmed by pathology in our hospital were selected,including 13 cases were benign and 46 cases were malignant,all underwent CDFI,SMI and CEUS examination.The sensitivity,specificity and accuracy of each examination method and multimodal ultrasound in the differential diagnosis of benign and malignant renal solid masses were compared.Receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic efficacy of each examination method and multimodal ultrasound in the differential diagnosis of benign and malignant renal solid masses.Results Among 59 patients,CDFI diagnosed 25 cases was benign and 34 cases was malignant,with a sensitivity of 67.39%,a specificity of 76.92%,and an accuracy of 69.49%.SMI diagnosed 20 cases was benign and 39 cases was malignant,with a sensitivity of 80.43%,a specificity of 84.62%,and an accuracy of 81.36%.CEUS diagnosed 28 cases was benign and 31 cases was malignant,with a sensitivity of 60.87%,a specificity of 76.92%,and an accuracy of 64.41%.Multimodal ultrasound diagnosed 13 cases was benign and 46 cases was malignant,with a sensitivity of 93.48%,a specificity of 76.92%,and an accuracy of 89.83%.ROC curve analysis results showed that the area under the curve(AUC)for CDFI,SMI and CEUS alone in the differential diagnosis of benign and malignant renal solid masses were 0.722,0.825 and 0.689,respectively.The AUC for multimodal ultrasound was 0.852.Conclusion Multimodal ultrasound has a certain clinical application value in the differential diagnosis of benign and malignant renal solid masses.
Ultrasonography,color,DopplerContrast agentSuperb microvascular imagingRenal solid masses,benign and malignantDifferential diagnosis
NETL
NSTL
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